diff --git a/packages/assets-controllers/CHANGELOG.md b/packages/assets-controllers/CHANGELOG.md
index 9419685a3e..b78c54edcc 100644
--- a/packages/assets-controllers/CHANGELOG.md
+++ b/packages/assets-controllers/CHANGELOG.md
@@ -9,6 +9,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ### Changed
 
+- Extend `TokenBalancesController` `isDeprecated` handling to `startPolling`, `updateChainPollingConfigs`, and `TransactionController:transactionConfirmed`, so polling and post-transaction balance fetches are skipped and stale `tokenBalances` are cleared when the controller is deprecated ([#9327](https://github.com/MetaMask/core/pull/9327))
 - Bump `@metamask/keyring-api` from `^23.1.0` to `^23.3.0` ([#9249](https://github.com/MetaMask/core/pull/9249))
 - Bump `@metamask/transaction-controller` from `^68.1.1` to `^68.2.0` ([#9253](https://github.com/MetaMask/core/pull/9253))
 - Bump `@metamask/multichain-account-service` from `^11.0.0` to `^11.1.0` ([#9264](https://github.com/MetaMask/core/pull/9264))
diff --git a/packages/assets-controllers/src/TokenBalancesController.test.ts b/packages/assets-controllers/src/TokenBalancesController.test.ts
index 56656ee144..f67e865e0b 100644
--- a/packages/assets-controllers/src/TokenBalancesController.test.ts
+++ b/packages/assets-controllers/src/TokenBalancesController.test.ts
@@ -2035,6 +2035,68 @@ describe('TokenBalancesController', () => {
 
       expect(controller.state.tokenBalances).toStrictEqual({});
     });
+
+    it('does not start polling and clears stale tokenBalances on startPolling when isDeprecated toggles to true at runtime', () => {
+      let deprecated = false;
+      const { controller } = setupController({
+        config: { state: initialState, isDeprecated: () => deprecated },
+      });
+
+      const executePollSpy = jest.spyOn(controller, '_executePoll');
+
+      deprecated = true;
+
+      controller.startPolling({ chainIds: ['0x1'] });
+
+      expect(executePollSpy).not.toHaveBeenCalled();
+      expect(controller.state.tokenBalances).toStrictEqual({});
+    });
+
+    it('does not restart polling and clears stale tokenBalances on updateChainPollingConfigs when isDeprecated toggles to true at runtime', () => {
+      jest.useFakeTimers();
+      let deprecated = false;
+      const { controller } = setupController({
+        config: { state: initialState, isDeprecated: () => deprecated },
+      });
+
+      controller.startPolling({ chainIds: ['0x1'] });
+
+      const executePollSpy = jest.spyOn(controller, '_executePoll');
+      executePollSpy.mockClear();
+
+      deprecated = true;
+
+      controller.updateChainPollingConfigs(
+        { '0x1': { interval: 60_000 } },
+        { immediateUpdate: true },
+      );
+
+      expect(executePollSpy).not.toHaveBeenCalled();
+      expect(controller.state.tokenBalances).toStrictEqual({});
+    });
+
+    it('does not fetch and clears stale tokenBalances on TransactionController:transactionConfirmed when isDeprecated toggles to true at runtime', async () => {
+      let deprecated = false;
+      const { controller, messenger } = setupController({
+        config: { state: initialState, isDeprecated: () => deprecated },
+      });
+
+      const fetchSpy = jest.spyOn(
+        multicall,
+        'getTokenBalancesForMultipleAddresses',
+      );
+
+      deprecated = true;
+
+      messenger.publish('TransactionController:transactionConfirmed', {
+        chainId: '0x1',
+      });
+
+      await flushPromises();
+
+      expect(fetchSpy).not.toHaveBeenCalled();
+      expect(controller.state.tokenBalances).toStrictEqual({});
+    });
   });
 
   describe('when accountRemoved is published', () => {
diff --git a/packages/assets-controllers/src/TokenBalancesController.ts b/packages/assets-controllers/src/TokenBalancesController.ts
index f04e5d7fc8..479741a290 100644
--- a/packages/assets-controllers/src/TokenBalancesController.ts
+++ b/packages/assets-controllers/src/TokenBalancesController.ts
@@ -516,13 +516,7 @@ export class TokenBalancesController extends StaticIntervalPollingController<{
 
     this.messenger.subscribe(
       'TransactionController:transactionConfirmed',
-      (transactionMeta) => {
-        this.updateBalances({
-          chainIds: [transactionMeta.chainId],
-        }).catch(() => {
-          // Silently handle balance update errors
-        });
-      },
+      this.#onTransactionConfirmed,
     );
   }
 
@@ -630,6 +624,10 @@ export class TokenBalancesController extends StaticIntervalPollingController<{
   };
 
   override _startPolling({ chainIds }: { chainIds: ChainIdHex[] }): void {
+    if (this.#isDeprecated()) {
+      this.#enforceDisabledState();
+      return;
+    }
     this.#requestedChainIds = [...chainIds];
     this.#isControllerPollingActive = true;
     this.#startIntervalGroupPolling(chainIds, true);
@@ -759,6 +757,10 @@ export class TokenBalancesController extends StaticIntervalPollingController<{
     configs: Record<ChainIdHex, ChainPollingConfig>,
     options: UpdateChainPollingConfigsOptions = { immediateUpdate: true },
   ): void {
+    if (this.#isDeprecated()) {
+      this.#enforceDisabledState();
+      return;
+    }
     Object.assign(this.#chainPollingConfig, configs);
 
     if (this.#isControllerPollingActive) {
@@ -1428,6 +1430,20 @@ export class TokenBalancesController extends StaticIntervalPollingController<{
     });
   };
 
+  readonly #onTransactionConfirmed = (transactionMeta: {
+    chainId: ChainIdHex;
+  }): void => {
+    if (this.#isDeprecated()) {
+      this.#enforceDisabledState();
+      return;
+    }
+    this.updateBalances({
+      chainIds: [transactionMeta.chainId],
+    }).catch(() => {
+      // Silently handle balance update errors
+    });
+  };
+
   readonly #onAccountChanged = (): void => {
     if (this.#isDeprecated()) {
       this.#enforceDisabledState();