diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index d47faaf..99a06e5 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -20,12 +20,10 @@ jobs:
     strategy:
       matrix:
         python:
-          - "3.10"
           - "3.11"
           - "3.12"
           - "3.13"
           - "3.14"
-          - "pypy-3.10"
           - "pypy-3.11"
           - "pypy-3.12"
     steps:
diff --git a/CHANGELOG.md b/CHANGELOG.md
index 1b6e1bc..d5713ef 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -20,6 +20,7 @@ For the purpose of determining breaking changes:
 
 ### :house: Internal
 
+- End of Python 3.10 support
 - Add tests for PyPy 3.12
 - Update dev dependencies
 
diff --git a/pyproject.toml b/pyproject.toml
index 741bbda..bd23e90 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -13,7 +13,6 @@ classifiers = [
     "Programming Language :: Python",
     "Programming Language :: Python :: 3",
     "Programming Language :: Python :: 3 :: Only",
-    "Programming Language :: Python :: 3.10",
     "Programming Language :: Python :: 3.11",
     "Programming Language :: Python :: 3.12",
     "Programming Language :: Python :: 3.13",
@@ -21,7 +20,7 @@ classifiers = [
     "Topic :: Utilities",
     "Topic :: Text Processing :: Markup :: XML",
 ]
-requires-python = ">=3.10"
+requires-python = ">=3.11"
 dependencies = [
     "defusedxml>=0.7.1",
     "typing-extensions>=4.6.0 ; python_version<'3.12'",
@@ -138,7 +137,7 @@ testpaths = ["docs", "tests"]
 
 [tool.ruff]
 src = ["src"]
-target-version = "py310"
+target-version = "py311"
 
 [tool.ruff.lint]
 select = ["ALL"]
diff --git a/src/bigxml/handle_mgr.py b/src/bigxml/handle_mgr.py
index 48f1997..384b4be 100644
--- a/src/bigxml/handle_mgr.py
+++ b/src/bigxml/handle_mgr.py
@@ -1,6 +1,5 @@
 from collections.abc import Callable, Iterable, Iterator
-import sys
-from typing import TYPE_CHECKING, Any, Optional, Union, overload
+from typing import TYPE_CHECKING, Any, Never, Optional, Union, overload
 
 from bigxml.handler_creator import create_handler
 from bigxml.typing import (
@@ -10,11 +9,6 @@
 )
 from bigxml.utils import last_item_or_none
 
-if sys.version_info < (3, 11):  # pragma: no cover
-    from typing_extensions import Never
-else:  # pragma: no cover
-    from typing import Never
-
 if TYPE_CHECKING:
     from bigxml.nodes import XMLElement, XMLText
 
diff --git a/tests/integration/test_typing.py b/tests/integration/test_typing.py
index fee4752..749d5cd 100644
--- a/tests/integration/test_typing.py
+++ b/tests/integration/test_typing.py
@@ -1,6 +1,6 @@
 from collections.abc import Iterable, Iterator
 from dataclasses import dataclass
-import sys
+from typing import Never, assert_type
 
 from bigxml import (
     HandlerTypeHelper,
@@ -11,12 +11,6 @@
     xml_handle_text,
 )
 
-if sys.version_info < (3, 11):
-    from typing_extensions import Never, assert_type
-else:
-    from typing import Never, assert_type
-
-
 # Note: the aim of this file is to test the typing of return-values
 # for iter_from and return_from as they would be used in the wild.
 # As a result, we don't try to factor code or do anything smart here.
diff --git a/tox.ini b/tox.ini
index 80b1833..4c58e55 100644
--- a/tox.ini
+++ b/tox.ini
@@ -2,7 +2,7 @@
 
 [tox]
 envlist =
-    py, py310, py311, py312, py313, py314, pypy3
+    py, py311, py312, py313, py314, pypy3
     build, docs, lint, type
 
 [testenv]