Search results

Support gradient-based fitting to parameter_scan (dose-response) objectives — reuse the per-point sensitivities already computed and discarded

Status: Open.

#476 In lanl/PyBNF;

· wshlavacek opened on Jul 12, 2026

Gradient fit aborts on incidental non-differentiable actions (unscored parameter_scan / non-ODE simulate)

Status: Open.

#475 In lanl/PyBNF;

· wshlavacek opened on Jul 12, 2026

Edition-2 experiment: can't express a pre-equilibration → intervention → dose-scan protocol (parameter_scan+preequil refused; no species setConcentration) — a published fit (Erickson 2019 IGF1R) is legacy-only

Status: Open.

#474 In lanl/PyBNF;

· wshlavacek opened on Jul 12, 2026

Add a small SSA end-to-end example to examples/real-world/ (fceri is cluster-scale)

Status: Open.

#472 In lanl/PyBNF;

· wshlavacek opened on Jul 11, 2026

Replace fixed 10-second waits during distributed-cluster startup and shutdown with real readiness checks

Status: Open.

#398 In lanl/PyBNF;

· wshlavacek opened on May 31, 2026

Feature request: Kalman-inspired proposals (DREAM-KZS)

Status: Open.

#358 In lanl/PyBNF;

· wshlavacek opened on Mar 27, 2026

Feature request: Multi-try DREAM (MT-DREAM) proposals

Status: Open.

#357 In lanl/PyBNF;

· wshlavacek opened on Mar 27, 2026